Titlebook: Hodgkin’s Disease in Children; Controversies and Cu W. A. Kamps,G. B. Humphrey,S. Poppema Book 1989 Kluwer Academic Publishers, Boston 1989

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Evidence for a B-cell origin of the proliferating cellsReed-Sternberg cells and a decrease in the lymphocyte admixture. The non-Hodgkin’s lymphomas have been demonstrated to be monoclonal proliferations of B- or T-lymphocytes, but in Hodgkin’s disease neither the cell of origin nor the monoclonal origin of the Reed-Sternberg cells has been established with certainty.

Phenothiazines

Treatment of childhood Hodgkin’s disease with chemotherapy aloneing decreased. In childhood Hodgkin’s disease, similar attempts are under way to eliminate the consequences of irradiation of growing tissues and postsplenectomy infections, and to reduce the cumulative toxicity of chemotherapy, surgery, and irradiation (Table 1).

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0927-3042 l­ ogy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimin­ ary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and publish

Cosmopolitan

The Sternberg-Reed cell normal counterpart of the SR cell. In this chapter, the most relevant opinions are summarized in an attempt to resolve some conflicting evidence regarding the SR cell origin, and thus also explain some other pecularities of the disease.

Institution

Late effects of Hodgkin’s disease treatment in children preventable or avoidable by modifying treatment, and (b) it is not often possible to escape altogether the risk of major complications. Since many of the late effects either threaten life or impair quality of survival, it is important to consider them in the selection of therapy.

Resection

Current management and controversiesbecause of the problems associated with this regimen (notably, sterility in males, the relatively high toxicity, the risk of second neoplasms, and a significant failure rate), other chemotherapy regimens are being studied.

Entropion

Current management and controversies The management of children requires utilization of not only principles that apply to the adult population, but also judgment with respect to age, stage, and extent of disease, tumor burden, therapeutic options, and late effects of treatment.

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https://doi.org/10.1007/978-1-4613-1739-5Staging; cancer treatment; cell; childhood; immunotherapy; leukemia; tumor

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