书目名称 | Histone Variants | 副标题 | Methods and Protocol | 编辑 | Guillermo A. Orsi,Geneviève Almouzni | 视频video | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .This volume compiles methodologies used for detailed studies of histone variants, from their basic properties to their functional roles in chromatin and as vectors of epigenetic information. Its four sections cover experimental approaches to probe the biochemistry of histone variants and variant nucleosomes; their dynamics throughout the cell cycle and at specific genomic locations; their functional impact on chromosome organization and genome stability; and their importance in development, disease and evolution. Written in the highly successful .Methods in Molecular Biology. series format, chapters include lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, illustrations on the expected results, and tips on troubleshooting and avoiding known pitfalls. This anthology brings together contributions from many of the most highly recognized investigators in this community..Cutting-edge and thorough, .Histone Variants: Methods and Protocols. is a valuable resource for anyone interested in exploring the experimental and collaborative possibilities in this evolving field.. | 出版日期 | Book 2018 | 关键词 | chromatin integrity; nucleosomes; histone chaperones; cellular functions; epigenomics | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-8663-7 | isbn_softcover | 978-1-4939-9358-1 | isbn_ebook | 978-1-4939-8663-7Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2018 |
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