Titlebook: Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy; Shabir Ahmad Ganai Book 2020 Springer Nature Singapore Pte Ltd. 2020 H

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Combining Histone Deacetylase Inhibitors with Other Anticancer Agents as a Novel Strategy for Circu when used singly (singlet therapy). Further the single agent use of these inhibitors escalates the probability of cancer cells for eliciting resistance mechanisms which in reciprocation hampers their therapeutic efficacy. Moreover, in singlet therapy the higher doses of HDACi used also sensitize th

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Overview of Epigenetic Signatures and Their Regulation by Epigenetic Modification Enzymes,e processes composing epigenesis. From this discussion, it becomes crystal clear that the term “epigenetics” is nothing but reminiscent of “epigenesis” and has been derived from union of two terms “epigenesis” and “genetics” (Waddington 1956). According to Waddingtonian equation, epigenetics = epige

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