Titlebook: Hepatitis B Virus and Liver Disease; Jia-Horng Kao Book 2021Latest edition The Editor(s) (if applicable) and The Author(s), under exclusiv

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Unmet Needs in Clinical Research Hepatitis B,y 30 million individuals (10%) are believed to have been diagnosed. A relatively small proportion of persons worldwide receive treatment. Deaths will increase in infected adults unless large increases in screening and a nexus to care are implemented. The age-specific disease burden is incompletely u

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Immunopathogenesis of Hepatitis B Virus Infection,s liver damage responsible for progression of disease. During acute HBV infection, the balance leans toward effective viral control with robust T and B cell immunity, limiting the duration of liver damage inflicted by the immune system and providing long-term immunity to the virus. During chronic in

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Pathology of Hepatitis B Virus (HBV) Infection and HBV-Related Hepatocellular Carcinoma,tion phases. These findings can often overlap with other viral and nonviral causes of hepatitis. Therefore, clinical information and serological findings are important in confirming the diagnosis of hepatitis B. Acute hepatitis B is not routinely biopsied as its histological findings are often nonsp

botany

TRACE

Epidemiology and Natural History of Hepatitis B Virus Infection: Time-Dependent Driving Factors of community-based cohort (such as REVEAL-HBV) studies and hospital-based cohort (such as ERADICATE-B) studies. They are considered to be the best choice for elucidating the natural history of the disease because of their long-term prospectiveness, wide range of disease severity, and comprehensive repe

Infect

Hepatitis B Vaccines, later from yeast cells using recombinant DNA technology. Hepatitis B vaccines have an overall efficacy of 80–100% and provide virtually complete protection against acute and chronic hepatitis B infection among persons who complete the three-dose vaccination series; a two-dose vaccine is now availab

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Viral and Host Factors Affecting Disease Progression of Hepatitis B Virus Infection,ntigen (HBsAg) to severe detrimental consequences, including hepatic failure, cirrhosis, and hepatocellular carcinoma (HCC). Four distinctive clinical phases are recognized in the natural course of chronic hepatitis B (CHB), namely, immune tolerance, immune clearance, inactive carrier and HBV reacti

avenge

Novel Biomarkers for the Management of Chronic Hepatitis B Virus Infection,ase progression of chronic hepatitis B virus (HBV) infection have been elucidated. For large-scale screening of chronic hepatitis B (CHB), point-of-care tests provide simple and rapid methods for HBV detection. Regarding the monitoring of CHB progression, hepatitis B core-related antigen (HBcrAg) an