Titlebook: Henipavirus; Ecology, Molecular V Benhur Lee,Paul A. Rota Book 2012 The Editor(s) (if applicable) and The Author(s), under exclusive licens

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Clinical and Pathological Manifestations of Human Henipavirus Infection,f severe, includes acute encephalitic and pulmonary syndromes with a high mortality. The pathological features in human acute henipavirus infections comprise vasculopathy (vasculitis, endothelial multinucleated syncytia, thrombosis), microinfarcts and parenchymal cell infection in the central nervou

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Henipaviruses in Their Natural Animal Hosts,igh case fatality rate following human infection and because of the lack of effective vaccines or therapy. Both viruses emerged from their natural reservoir during the last decade of the twentieth century, causing severe disease in humans, horses and swine, and infecting a number of other mammalian

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Diagnosis of Henipavirus Infection: Current Capabilities and Future Directions,st development, especially in the development of molecular tests using real-time PCR and many novel serological test platforms. In addition to provide an updated review of the current test capabilities, this review also identifies key future challenges in henipavirus diagnosis.

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Immunization Strategies Against Henipaviruses,y . and are distinguished by their broad species tropism and in addition to bats can infect and cause fatal disease in a wide variety of mammalian hosts including humans. The high mortality associated with human and animal henipavirus infections has highlighted the importance and necessity of develo

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Henipaviruses in Their Natural Animal Hosts,ervoir during the last decade of the twentieth century, causing severe disease in humans, horses and swine, and infecting a number of other mammalian species. The current review summarizes our up to date understanding of pathology and pathogenesis in the natural reservoir species, the . bat, and in the equine and porcine spill over species.

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