Titlebook: Heme and Hemoproteins; Francesco Matteis,W. Norman Aldridge Book 1978 Springer-Verlag Berlin Heidelberg 1978 Arzneimittelnebenwirkung.Bili

COKE

Loss of Liver Cytochrome P-450 Caused by Chemicals,hat of cytochrome P-450); this is one aspect of the more general adaptive response, usually referred to as induction of the drug-metabolizing system, which has been dealt with by . and . in Chapter 2. There are cases, however, in which a chemical causes a decrease rather than an increase in the conc

VEST

甜瓜

yohimbine

The Effect of Chemicals on Hepatic Heme Biosynthesis,shown to be the major site of the metabolic disturbance contained large amounts of uro-, copro-, and proto-porphyrin. Sedormid (Fig. 1 a) has a structure closely similar to the barbiturate group of drugs (Fig. 1 b). Investigation of the relationship between structure and porphyrin inducing activity

宽宏大量

Pharmacogenetics in the Field of Heme Metabolism: Drug Sensitivity in Hereditary Hepatic Porphyria,ed by genetically determined aberrations in metabolic pathways. This far-sighted observation was neglected for many years. However, with the recognition in the 1950’s that several “idiosyncratic” drug reactions, such as primaquine-induced hemolytic anemia and suxamethonium-induced prolonged apnoea,

acolyte

不自然

执

coddle

表皮