| 书目名称 | Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection |
| 编辑 | Alexzander A.A. Asea,Ian R. Brown |
| 视频video | |
| 概述 | Written by leaders in the field of neurodegenerative diseases and neuroprotection.Provides up-to-date reviews on the most recent concepts of the role of heat shock proteins in repair and protective me |
| 丛书名称 | Heat Shock Proteins |
| 图书封面 |  |
| 描述 | With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pressing challenge. Neurodegenerative disorders such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and amyotrophic lateral sclerosis have been termed ‘protein misfolding disorders’ that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV). Key basic and clinical research laboratories from major u |
| 出版日期 | Book 2008 |
| 关键词 | Chaperones; HSP; Nervous System; Parkinson; Protein folding; Stress proteins; neurons |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4020-8231-3 |
| isbn_softcover | 978-90-481-7813-1 |
| isbn_ebook | 978-1-4020-8231-3Series ISSN 1877-1246 Series E-ISSN 1877-1254 |
| issn_series | 1877-1246 |
| copyright | Springer Science+Business Media B.V. 2008 |
发表于 2025-3-21 19:05:26
