书目名称 | Handbook on Immunosenescence | 副标题 | basic understanding | 编辑 | Tamas Fulop,Claudio Franceschi,Graham Pawelec | 视频video | | 概述 | The first comprehensive handbook on immunosenescence.First to treat in one volume all the aspects of immunosenescence.Bridging bench research and clinical applications.Written by internationally recog | 图书封面 |  | 描述 | .“Immunosenescence” is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. We are poised to be in a position to translate these accumulated data into the clinical setting via better understanding of the contribution of immunosenescence to age-associated pathologies, and their prevention by appropriate interventions. This authoritative handbook seeks to encompass the current state of our knowledge on the multitude of those changes to immunity related to aging, with contributions from experts in the research and clinical areas. This book therefore considers methods and models for studying immunosenescence; cellular immunosenescence of T cells, B cells, neutrophils, antigen presenting cells, NK, NKT and stem cells; genetics; mechanisms including receptors and signal transduction; mitochondria; proteasome; cytokines; neuro-endocrine-immune networks; inflammation; thymus; clinical relevance in disease states including infections, autoimmunity, cancer, metaboli | 出版日期 | Book 2009 | 关键词 | Antigen; Immunosenescence and clinical applications; Thymus; aging; cancer; frailty; infections; metabolic | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4020-9063-9 | isbn_softcover | 978-94-017-7721-6 | isbn_ebook | 978-1-4020-9063-9 | copyright | Springer Science+Business Media B.V. 2009 |
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