Titlebook: Handbook of Schizophrenia Spectrum Disorders, Volume I; Conceptual Issues an Michael S. Ritsner Book 2011 Springer Science+Business Media B

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Diagnosis and Classification of the Schizophrenia Spectrum Disorders,ementia praecox from manic-depression, heralding the diagnosis of schizophrenia as a separate entity, but this distinction has since been challenged by data from genetic epidemiology. Over the past century, two major classification systems emerged: the American Psychiatric Association’s Diagnostic a

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Toward a Multidimensional Continuum Model of Functional Psychoses for Research Purposes,called “functional psychoses” (FP). The paradigm, underlying the current model of FP, was based on Kraepelinian dichotomy and was a practical starting point for the categorical classification of FP. Nevertheless, the concept is increasingly challenged by emerging data from modern research in the fie

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Schizotypy: Reflections on the Bridge to Schizophrenia and Obstacles on the Road Ahead to Etiology ychopathology and the underlying liability for schizophrenia. This liability is termed schizotypy and represents a unifying latent construct that gives rise to both psychopathologies. Schizotypy can manifest itself in a variety of forms ranging from flagrant schizophrenia through less conspicuous sc

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Autistic Spectrum Disorders and Schizophrenia,on, and repetitive behaviors. With a progressive evolution in understanding this unique group of disorders, a variety of phenotypes have been postulated, with variability in both biological features and response to treatment. Etiologically, autism is believed to involve a genetic predisposition that

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One Hundred Years of Insanity: Genomic, Psychological, and Evolutionary Models of Autism in Relational reality in patients with schizophrenia, almost exactly a century ago. Ever since 1943 when Leo Kanner co-opted “autism” to refer to a new condition involving “disturbance of affective contact” manifested in children, the relationship between schizophrenia and Kanner’s autism has remained unclear

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,Amino Acids in Schizophrenia – Glycine, Serine and Arginine,his research has focused on glutamate and γ-aminobutyric acid (GABA), and these are the subjects of other chapters in this book. However, there have also been interesting findings reported with glycine, serine (particularly D-serine) and arginine, and this chapter provides a brief overview of those