Titlebook: Handbook of Multiple Sclerosis; Jeffrey A. Cohen,Alexander Rae-Grant Book 2012Latest edition Springer Healthcare, a part of Springer Scien

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Symptom Management,their severity vary markedly from patient to patient and in individual patients over time. MS symptoms can interfere with daily activities or lessen quality of life (QOL), and many are amenable to treatment. Thus identification and treatment of symptoms is an important aspect of MS management.

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Jeffrey A. Cohen,Alexander Rae-GrantDie Defizite der typischen Neuroleptika in Bezug auf die Verträglichkeit sind Argumente für den Einsatz moderner Antipsychotika. Dass eine unmittelbare Umstellung möglich ist, zeigen die Ergebnisse einer multizentrischen Phase-III-Studie [1].

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Clinical Features,The wide range of symptoms and signs of multiple sclerosis (MS) reflect multifocal lesions in the central nervous system (CNS), including in the afferent visual pathways, cerebrum, brainstem, cerebellum, and spinal cord (Figure 2.1).

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Diagnosing Multiple Sclerosis,Making an accurate and expeditious diagnosis of multiple sclerosis (MS) is important to allow the timely institution of disease-modifying therapy. Accurate diagnosis also removes uncertainty, and allows informed career and family planning. However, with the push to make the diagnosis early, there is increased risk of misdiagnosis.

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Treatment of Acute Relapses of Multiple Sclerosis,The evaluation and treatment of acute multiple sclerosis (MS) relapses has several aspects.

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Disease-Modifying Therapy,Since 1993 eight disease-modifying agents have been approved by regulatory agencies to treat relapsing–remitting multiple sclerosis (RR MS). In addition, a sizable number of agents are used off label alone or in combination.