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Titlebook: Handbook of Glycosyltransferases and Related Genes; Naoyuki Taniguchi (Professor),Koichi Honke (Associ Book 20021st edition Springer Japan

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β3-Galactosyltransferase-IV (GM1 Synthase)ther enzymes (genes) catalyzing similar functions have been detected to date. In the mouse genome (. major histocompatibility locus class II region), a highly homologous gene as an orthologue to rat β3-galactosyltransferase-IV was reported by Rowen et al. (see AF100956, AF110520).
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GalCer Synthase (Ceramide Galactosyltransferase, CGT)s. Both are expressed in only a minute amount in kidney. The molar ratio of cholesterohphospholipids (including plasmalogen-phospholipids):galactolipids is between 2:2:1 and 4:3:2 and reasonably stable in different species (human, bovine, and murine myelin).
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-Acetylglucosaminyltransferase-IIdase II to form the substrate for GnT-II (.). GnT-II transfers GlcNAc from UDP-α-GlcNAc in the β1,2-linkage to the Manα1-6 arm of the .-glycan core, and is essential for normal complex .-glycan formation (.).
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ar differentiation and developmental events, as well as in disease processes. Over 300 glycosyltransferases appear to exist in mammalian tissues. If the genes that have been purified and cloned from various species such as humans, cattle, pigs, rats 978-4-431-67877-9
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GlcCer Synthase (UDP-Glucose:Ceramide Glucosyltransferase, UGCG)f the gene encoding GlcT-I has provided new insights into the previously unrecognized roles of GSLs (.). When the GlcT-I function is knocked out in mice by gene-targeting technology, the mouse dies at embryonic day 8 (.). This study clearly shows that GlcT-I plays an essential role during embryonic
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β4-Galactosyltransferase-II, -III, -IV, -V, -VI, and -VIIl Galβ1→4GlcNAc groups found in the .-linked oligosaccharides of the mutant mouse (.; .; .). Since Lewis X-containing oligosaccharides inhibited the compaction of mouse embryos (.), and since a β4GalT-knockout mouse can survive beyond birth (.; .), the galactose-containing oligosaccharides synthesiz
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α3-Galactosyltransferase shows extensive sequence similarity to three other GTs (blood group A and B transferase; Forssman glycolipid synthase), and can be grouped with these enzymes in one GT family. The enzyme is expressed in most mammals, with the notable exception of man, apes, and Old World monkeys.
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