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Titlebook: Handbook of Downstream Processing; Elliott Goldberg (Director of Process Engineering) Book 1997 Chapman & Hall 1997 Downstream Processing.

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发表于 2025-3-21 18:28:07 | 显示全部楼层 |阅读模式
书目名称Handbook of Downstream Processing
编辑Elliott Goldberg (Director of Process Engineering)
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图书封面Titlebook: Handbook of Downstream Processing;  Elliott Goldberg (Director of Process Engineering) Book 1997 Chapman & Hall 1997 Downstream Processing.
描述The last two decades have seen a phenomenal growth of the field of genetic or biochemical engineering and have witnessed the development and ultimately marketing of a variety of products-typically through the manipulation and growth of different types of microorganisms, followed by the recovery and purification of the associated products. The engineers and biotechnologists who are involved in the full-scale process design of such facilities must be familiar with the variety of unit operations and equipment and the applicable regulatory requirements. This book describes current commercial practice and will be useful to those engineers working in this field in the design, construction and operation of pharmaceutical and biotechnology plants. It will be of help to the chemical or pharmaceutical engineer who is developing a plant design and who faces issues such as: Should the process be batch or continuous or a combination of batch and continuous? How should the optimum process design be developed? Should one employ a new revolutionary separation which could be potentially difficult to validate or use accepted technology which involves less risk? Should the process be run with ingredi
出版日期Book 1997
关键词Downstream Processing; Fermenter; Lysin; biochemical engineering; biotechnology; chromatography; filtratio
版次1
doihttps://doi.org/10.1007/978-94-009-1563-3
isbn_softcover978-94-010-7198-7
isbn_ebook978-94-009-1563-3
copyrightChapman & Hall 1997
The information of publication is updating

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Product recovery and purification via precipitation and crystallization,cts, both crystallization and precipitation are more similar than different. However, some differences exist and will be highlighted during the subsequent discussion. Although many of the examples presented in this chapter will focus on the application to protein molecules, the principles applied may be generalized to any system.
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Richard Willstätter,Werner Steibeltes exist, the one most often used is distillation. Distillation is simple, has few moving parts, is well understood, can be simulated readily, and often has a low capital cost. On the negative side is the high operating cost associated with high energy requirements to vaporize and condense.
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Controls and automation for biotechnology and pharmaceutical industries,sizes of 9 m (30 ft approx) or longer, a common occurrence, and operators had to move around in order to see all process variables. Additions or change to pneumatic control loops were extremely difficult and expensive.
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