Titlebook: Handbook of Chemical Biology of Nucleic Acids; Naoki Sugimoto Living reference work 20220th edition DNA.RNA.Riboswitch.Ribozyme.Quadruple

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y used in various technical applications using nucleic acids. Thermodynamics for the structural changes is highly useful and important for understanding the biological mechanism of nucleic acid function, as well as for the design of materials for nucleic acids. The canonical structure of nucleic aci

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ze the canonical and noncanonical DNA structures. Under most solution conditions, double- and triple-stranded DNA molecules are stabilized to a small extent by increasing pressure regardless of their nucleotide sequence. On the other hand, the stabilities of noncanonical conformations, including hai

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Robin Ivy Osterkamp,Friederike Wünschbiochemical studies. Knowledge of the structure and dynamics of nucleic acids is important not only for understanding biological mechanisms, but also for developing new therapeutics. NMR (Nuclear Magnetic Resonance) spectroscopy has been used for many years to determine the structure of nucleic acid

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Trans-Cultural Leadership Developmentarea of research in telomere, gene regulation, and functional genomics research. Investigation of G-quadruplex structures associated with biological events is therefore essential to understanding the functions of these molecules. Antibodies and some small molecules have been used to investigate DNA

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Trans-European Energy Networks,raction between them at the atomic level is expected to provide valuable information for revealing the molecular mechanism responsible for the regulation of diverse biological processes through their interaction. Heme binds selectively to the 3’-terminal G-quartet of a parallel G-quadruplex DNA to f