Titlebook: HRT and Osteoporosis; James O. Drife (Professor of Obstetrics and Gynaec Conference proceedings 1990 Springer-Verlag London Limited 1990 O

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Biology of the Menopauseeeding is deemed to have occurred. Ovarian failure is an integral part of the menopause; amenorrhoea due to lack of pituitary gonadotrophins or removal of the uterus with conservation of the ovaries is not usually included in the menopausal state.

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Endocrinology and Osteoporosis these processes are hormonal, it is necessary to have an understanding of the effect of hormones on bone to understand both normal bone physiology and also the deleterious effects on the skeleton of many endocrine disorders.

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Psychological Effects of the Menopauset the menopause is exceptionally high. Second, menopausal depression is said to have special causes, notably lack of oestrogen. Third, the treatment of menopausal depression is said to be special, particularly in relation to the indications for hormone replacement therapy. The aim of this chapter, therefore, is to examine three questions:

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re is an important cause of osteoporosis and that much of the bone loss after the menopause can be prevented by oestrogen treatment. There is now an urgent need on the part of women, their doctors and those responsible for public health policy for practical guidance on such questions as the safety a

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