| 书目名称 | HDAC/HAT Function Assessment and Inhibitor Development |
| 副标题 | Methods and Protocol |
| 编辑 | Oliver H. Krämer |
| 视频video | |
| 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | This fully updated edition provides a series of methods for how best to assess functions of histone deacetylases and acetyltransferases. The disease-relevance of dysregulated protein deacetylation by overexpressed or aberrantly activated histone deacetylases has spurred an intense search for novel and improved inhibitors of these enzymes, as reflected in this collection. Expert contributors explore the generation and evaluation of novel histone deacetylase inhibitors and new and improved techniques to assess acetylation-dependent molecular mechanisms in vitro and in vivo. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and up-to-date, .HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols, Second Edition. serves as an ideal guide for researchers seeking to further elucidate this vital area of study.. |
| 出版日期 | Book 2023Latest edition |
| 关键词 | Histone deacetylases; Histone acetyltransferases; Protein acetylation and deacetylation; Dysregulated p |
| 版次 | 2 |
| doi | https://doi.org/10.1007/978-1-0716-2788-4 |
| isbn_softcover | 978-1-0716-2790-7 |
| isbn_ebook | 978-1-0716-2788-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 19:12:16
