Titlebook: ;

完整

Three-Dimensional Extracellular Matrix Protein Hydrogels for Human Trabecular Meshwork Cell Studiesnt a realistic three-dimensional extracellular milieu to cells in vitro. Here, we describe the fabrication and use of soft tissue-mimetic extracellular matrix protein hydrogels for investigations of human trabecular meshwork cell biology.

内疚

含铁

Measurements of Phagocytosis in Trabecular Meshwork Cells,Among the functions of the trabecular meshwork that help to prevent this restriction and maintain the movement of aqueous humor is phagocytosis. Cells in the trabecular meshwork actively phagocytose pigment, cellular debris, and other materials in order to help keep the drainage pathway clear. A dec

Breach

Nanotubules and Cellular Communication in Trabecular Meshwork Cells,hogenesis, where decreased TM cell numbers and alterations to the amount and composition of extracellular matrix hinder outflow of aqueous humor fluid from the anterior chamber. This causes intraocular pressure (IOP) elevation. Elevated IOP, a main risk factor for primary open-angle glaucoma, damage

声明

laparoscopy

Time-Lapse Live-Cell Imaging Using Fluorescent Protein Sensors in Outflow Pathway Cells Under FluidSC) of the eye is an emerging field. Shear stress has been shown to activate mechanosensitive ion channels in TM cells and induce nitric oxide production in SC cells, which can affect outflow resistance and lower IOP. Live-cell imaging using fluorescent protein sensors has provided real-time data to

尽管

Human Anterior Segment Perfusion Organ Culture,essure regulation. In this model, anterior segments dissected from human donor eyes can be fixed to a modified petri dish and perfused with media along with various study agents at the physiological flow rate of 2.5 μL/min. The model mimics the one-way flow of aqueous humor in human eyes and can be

AORTA

担忧

Human Corneal Rim Perfusion Culture,es which are expensive. Here, we describe a method using human corneal rims as an alternative to anterior segments for perfusion culture. In this method, the human corneal rim is glued to a three-dimensional-printed perfusion plates instead of using mechanical compression in traditional perfusion cu

残暴

,The Inducible TGFβ2 Ocular Hypertension Mouse Model,at produces a homogeneous intraocular pressure (IOP) response and can be induced in any mouse strain of choice without the need for extensive breeding. The procedure utilizes an ocular hypertension and glaucoma-relevant transgene, bioactivated TGFβ2, and an adenovirus 5 virus with select tropism for