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Imke Friedrich,Wilfried Rudloffhese changes at the molecular level is largely unclear. The use of supranormal temperatures has been found to induce striking changes on the nuclear level (12). In this respect it is of interest to study the modifications of chromatin by hyperthermia at successive stages of the cell cycle. One appro
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Interessengruppen in Niedersachsenreakdown and chromosome condensation. Three specific proteins of the nuclear lamina, called lamins, become highly phosphorylated attendent to nuclear dissolution, and then are dephosphorylated as the nuclear membrane reforms (1). Concomitantly, histones become highly phosphorylated as chromosomes co
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https://doi.org/10.1007/978-3-658-13689-5h the tumor promoter 12–0-tetradecanoylphorbol-l3-acetate, TPA, itself is not mitogenic, it can enhance the response of bovine lymphocytes to lectins by acting as an analogue of interleukin 1 (2). Thus, in the presence of a suboptimal dose of ConA or a limiting number of macrophages, TPA allows full
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https://doi.org/10.1007/978-3-531-91134-2long periods of time in a viable but nondividing state. This phenomenon, termed density-dependent inhibition of growth (2), was first described and most extensively studied in the 3T3 cell line. In this paper we review some recent evidence indicating that endogenous growth inhibitors may account for
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A Rat Liver Helix-Destabilizing Protein: Properties and Homology to LDH-5 helix-destabilizing activity, and present surprising evidence which indicates extensive structural and functional homology between this rat liver helix-destabilizing protein (HDP) and lactic dehydrogenase-5 (LDH-5) from various sources.
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