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Regulation of Nerve Growth Factor Synthesis in the Central Nervous System by Cytokines and Implicattigated the changes in NGF synthesis which occurred in cultured rat astrocytes and in the hippocampus after intraventricular injection of various growth factors and cytokines. We found that in particular, interleukin-1 (IL-1) and transforming growth factor β (TGF-β) enhanced the synthesis of NGF bot
发表于 2025-3-30 18:07:41 | 显示全部楼层
Nerve Growth Factor Expression and Function in the CNS,sed into aged and young rats. In young adult rats, chronic NGF infusion produces robust increases in APP mRNA hybridization, NGFr mRNA hybridization, NGFr immunoreactivity, ChAT mRNA hybridization, and hypertrophy of ChAT immunoreactivity and mRNApositive neurons. NGF treatment also increases the ra
发表于 2025-3-31 00:38:01 | 显示全部楼层
Nerve Growth Factor and Behavioral Recovery After Brain Damage in Rats,gle intrahippocampal injection of NGF made at the time of lesion surgery. Behavior was measured in a test battery including spontaneous alternation and radial maze performance. The results were as follows:
发表于 2025-3-31 02:20:22 | 显示全部楼层
Functional Impairments that Develop in Nerve Growth Factor-Sensitive Neuronal Projections in the PNged animal constitutes a partial model of this disease. Therefore, we have looked for evidence of a naturally occurring deficit in NGF utilisation in aged rats both in the PNS, by measuring cutaneous sensory fields, and in the CNS of the same animals, by using the Morris water maze to reveal possibl
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