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Group-Sequential Clinical Trials with Multiple Co-Objectives978-4-431-55900-9Series ISSN 2191-544X Series E-ISSN 2191-5458
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https://doi.org/10.1057/9781137326256y of the design assumptions and potentially make design adjustments if the assumptions are markedly inaccurate. We discuss sample size recalculation based on the observed intervention’s effects during interim analyses with a focus on the control of statistical error rates.
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Philanthropy and the National Park Servicemplest procedure, i.e., the weighted Bonferroni procedure which is commonly applied in practice. We evaluate the behavior of the sample size, power, and Type I error rate associated with the procedure.
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Interim Evaluation of Efficacy in Clinical Trials with Two Co-primary Endpoints,valuation of superiority not necessarily simultaneously and (B) evaluation of superiority for the two primary endpoints simultaneously. We evaluate the behaviors of sample size and power with varying design characteristics and provide an example to illustrate the methods.
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2190-3018 -Agent Systems: Technologies and Applications (KES-AMSTA 201.This book gathers the proceedings of the KES-IDT-2018 conference, held in Gold Coast, Queensland, Australia, on June 20–22, 2018 The conference provided opportunities to present and discuss the latest research results, promoting knowledge
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