书目名称 | Glycosylation Engineering of Biopharmaceuticals |
副标题 | Methods and Protocol |
编辑 | Alain Beck |
视频video | http://file.papertrans.cn/388/387118/387118.mp4 |
概述 | Presents detailed protocols on the production and characterization of glycoproteins and glyco-engineered biopharmaceuticals.Contains a special focus on monoclonal antibodies (mAbs).Features expert tip |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | .Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In .Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols., experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful .Methods in Molecular Biology™. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.. .Authoritative and cutting-edge, .Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols. serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals. |
出版日期 | Book 2013 |
关键词 | Biopharmaceuticals; Glyco-engineering; Glycoanalytics; Glycoproteins; Monoclonal antibodies; PK/PD assays |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-62703-327-5 |
isbn_softcover | 978-1-4939-6266-2 |
isbn_ebook | 978-1-62703-327-5Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media New York 2013 |