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Titlebook: Glycosignals in Cancer: Mechanisms of Malignant Phenotypes; Koichi Furukawa,Minoru Fukuda Book 20161st edition Springer Japan 2016 Glycosy

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rested in cancers and carbohydrates. Specialists in glycobiology will also benefit from the new results and approaches detailed here, which provide insights into future directions of functional studies of sugar chains in both basic and applied research..978-4-431-56732-5978-4-431-55939-9
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Glycosyltransferases and Gastric Cancercell adhesion molecules and signaling pathways, and the glycan-mediated modulation of cell biological functions are also discussed..The decoding of the functional role of glycans in gastric cells may constitute the basis for defining biomarkers with potential to improve diagnosis and prognosis, cont
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Differential Roles of Mammalian Sialidases in Cancersnitiation, promotion, and progression. Human sialidases, thus, may provide potential targets for cancer diagnosis and therapy. The present review briefly summarizes our recent results on aberrant expression and roles of mammalian sialidases in cancers.
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Regulation of Growth Factor Receptors by Glycosphingolipidsomains. There is increasing evidence that GSLs modulate the activation of GFR kinases in such microdomains, in which other signaling molecules and regulatory molecules such as integrins and tetraspanins are also localized.
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Role of Glycans in Cancer Cell Death: A Deadly Relationshipycans, and the enzymes that synthesize these glycans, may be partly responsible for the malfunctioning of apoptosis pathways. In particular, sialic acids and specific sialyltransferases are potential therapeutic targets to increase cell death..However, it is necessary to consider the glycosylation p
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Glycosignals in Cancer: Mechanisms of Malignant Phenotypes978-4-431-55939-9
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