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Titlebook: Glycosignals in Cancer; Molecular Assembly a Koichi Furukawa,Minoru Fukuda Book 2023Latest edition Springer Nature Singapore Pte Ltd. 2023

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Insights into the Role of Chondroitin Sulfate in Cancerare covalently attached to the serine (Ser) residues of core proteoglycan proteins. The expression levels and/or fine structure of CS chains are altered in response to environmental cues, and such changes are involved in controlling cell fate decisions. CS chains selectively interact with numerous p
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Significance of FUT8 in Pancreatic Cancer and Othersel of core fucosylation has been observed. Core fucosylation is driven by fucosyltransferase 8 (FUT8), which catalyzes transfer of the fucosyl moiety from GDP-fucose to the innermost GlcNAc residue of .-glycans via an α1,6-linkage. Core fucosylation is known to be critical for various biological pro
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Effects of Bullfrog Sialic Acid–Binding Lectin in Cancer Cellsed by sialic acid–containing glycoconjugates. The lectin was subsequently found to belong to the vertebrate-secreted ribonuclease family, and cSBL exhibits ribonuclease activity as well as remarkable antitumor effects. Recent studies have shown that cSBL exerts antitumor effects in vitro and in vivo
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Tumor Progression through Interaction of Mucins with Lectins and Subsequent Signal Transduction are typically expressed on mucins. Some lectins recognizing these antigens have been identified mainly on immune cells and play a role as inhibitory receptors..Binding of soluble lectins and/or membrane-bound lectins (lectin receptors) to membrane-bound mucins such as MUC1 triggers signaling in tum
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Tumor Progression through Interaction of Mucins with Lectins and Subsequent Signal Transductionnt data on MUC1-mediated signaling through interactions with galectin-3 and Siglec-9, and then review lectin receptor-mediated signaling triggered by binding of mucins and its biological significance.
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Book 2023Latest editiongh analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pat
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