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Titlebook: Glycoprotein Hormones; Structure, Function, Joyce W. Lustbader,David Puett,Raymond W. Ruddon Conference proceedings 1994 Springer-Verlag Ne

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书目名称Glycoprotein Hormones
副标题Structure, Function,
编辑Joyce W. Lustbader,David Puett,Raymond W. Ruddon
视频video
丛书名称Serono Symposia USA
图书封面Titlebook: Glycoprotein Hormones; Structure, Function, Joyce W. Lustbader,David Puett,Raymond W. Ruddon Conference proceedings 1994 Springer-Verlag Ne
描述Advances in the field of glycoprotein hormones necessitated a second international symposium on this topic, held March 11 to 14, 1993, in Santa Barbara, California, and again sponsored by Serono Symposia, USA. The meeting was twofold in its concept: (1) the dissemination of the current research in the field and (2) honoring three scientists who have greatly contributed to this field, Drs. Harold Papkoff, Robert Ryan, and Darrell Ward, upon their retirements. We were honored to have Dr. John Pierre present as a participant at the meeting and also serving as master of ceremonies at the banquet. Certainly one of the highlights at the first meeting, held in 1989, was the cloning of the CG/LH receptor. This second meeting was also filled with insightful and innovative scientific presentations. Significant advances in the regulation of gene transcription of the gonadotropins were presented by Pamela Mellon, James Hoeffler, John Nilson, Bruce Weintraub, and Joel Habener. These presentations reflected major advances from the in the understanding concepts offered at the last meeting. Other advances of hormone structure/function included the continuing work by Joyce Lustbader on the determin
出版日期Conference proceedings 1994
关键词Expression; Protein; Regulation; Translation; gene expression; metabolism; tertiary structure; transcriptio
版次1
doihttps://doi.org/10.1007/978-1-4613-8386-4
isbn_softcover978-1-4613-8388-8
isbn_ebook978-1-4613-8386-4
copyrightSpringer-Verlag New York, Inc. 1994
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Endocrine Regulation of Glycoprotein Hormone Alpha Subunit Gene Expression in Transgenic Micedistinct beta subunits that confer biological specificity (1). The common alpha subunit and each of the beta subunits are encoded by unique single copy genes that are expressed in specific cell types (gonadotropes: LH and FSH; thyrotropes: TSH) of the anterior pituitary gland (1, 2). LH and FSH are
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Coordinate Regulation of the Gonadotropin Subunit Genes in Pituitary and Placentadinately expressed with an individual β-subunit gene to form each hormone (2). The . (CG) β-subunit gene is coexpressed with the α-subunit gene in placental trophoblasts, while the thyroid stimulating hormone β-subunit gene is coexpressed with the α-subunit gene in pituitary thyrotropes. In pituitar
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Role of Helix-Loop-Helix Proteins in Gonadotropin Gene Expressiones can occur at almost any point along the pathway from DNA to protein. The most common method that cells use to express specialized genes is to regulate the level of transcription of these genes (1). Combinations of transcription-enhancing and -repressing DNA binding factors can determine the level
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Regulation and Expression of Thyroid Stimulating Hormonen common with the gonadotropins, luteinizing hormone, and follicle stimulating hormone; and the unique beta subunit, which confers biological specificity to the intact hormone and is expressed exclusively in the thyrotropes of the anterior pituitary (2). Previous studies have indicated that the tran
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Evidence for Altered Splicing in Two Members of the Chorionic Gonadotropin β Gene Clusterng the . (FT). CG is a member of the glycoprotein hormone family that includes the pituitary hormones . (LH), follitropin, and thyrotropin and consists of an α.β heterodimer. The α-subunit is encoded by a single gene (1) and the β-subunit is encoded by a cluster of six genes (or pseudogenes [2, 3])
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