Titlebook: Glutamate and Neuropsychiatric Disorders; Current and Emerging Zoran M. Pavlovic Book 2022 Springer Nature Switzerland AG 2022 Aggression.A

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Current Glutamatergic Treatments and Future Directions for Glutamate-Based Management of Chronic Stsion in adults and its quick introduction in everyday psychiatric practice might be considered as a second revolution in the field of neuropsychopharmacology after the first one, which started over 50 years ago with the discovery of the monoaminergic antidepressants. This chapter will present the cr

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The Role of the Glutamate System in Posttraumatic Stress Disorder and Glutamate-Based Treatments,dance, hyperarousal, emotional numbing, and anhedonia. PTSD is often triggered by exposure to a single traumatic experience, with high prevalence among war veterans. PTSD, together with other neuropsychiatric disorders, involves long-term changes in the structure and function of brain areas, synapti

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The Glutamatergic System as a Target for the Development of New Pharmacological Treatments of Bipolabilizers used to treat it are not always sufficient for all patients and typically depression in patients with bipolar disorder (BD) is not well responding to antidepressants. Glutamate is the major excitatory neurotransmitter of the CNS and is present in more than 50% of nerve tissue. The relation

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,Glutamatergic Treatments for Parkinson’s Disease,n-motor symptoms. The current knowledge demonstrates that the activity of glutamatergic signals from the cortex to the striatum is strictly regulated during the progression of the disease and indicates that modulation of synaptic transmission at the glutamatergic synapse represents a major target to

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The Modulation of Glutamatergic Signaling as a Potential Therapeutic Strategy for Major Depression, a potential therapeutic strategy for Major Depressive Disorder (MDD), from animal models to recent phase III clinical trials. The main clinical features of MDD, its epidemiological impact in terms of disease burden, its mainstream pharmacological treatment, and current unmet needs are presented. A