Titlebook: Glucocorticoids; Nicolas J. Goulding,Rod J. Flower Book 2001 Springer Basel AG 2001 autoimmune disease.biology.drug.drug development.endoc

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2296-6056 rticoid-based therapeutics. Scientists and clinicians will appreciate the scope of this work, which is of special interest to workers in the fields of endocrinology, inflammation and autoimmune disease.978-3-0348-9528-6978-3-0348-8348-1Series ISSN 2296-6056 Series E-ISSN 2296-6064

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The glucocorticoid receptor: expression, function, and regulation of glucocorticoid responsivenessglucocorticoid receptor (GRα). GRα belongs to the superfamily of steroid/thyroid/retinoic acid receptor proteins that function as ligand-depend-ent transcription factors [.], Following high affinity binding of the glucocorticoid hormone, GRα activates or represses transcription of target genes and consequently changes cellular phenotype.

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Systemic glucocorticoids in chronic arthritisnti-inflammatory properties of glucocorticoids) used them in rheumatoid arthritis (RA) with dramatic results [1]. The subsequent widespread use of glucocorticoids as anti-inflammatory agents made its mark in many conditions, with an inflammatory or auto-immune basis.

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Learn iOS Application DistributionBronchial asthma is primarily a chronic inflammatory disease of the bron-chopulmonary airways associated with an intramural infiltration of lymphocytes and eosinophils, and an excess production of T. type cytokines.

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