Titlebook: Gliomas; Andreas Deimling Book 2009 Springer-Verlag Berlin Heidelberg 2009 Astrocytic tumors.Ependymal tumors.Oligodendroglial tumors.Pedi

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Hospitalized Chronic Pain Patientecurrence in brain tumors. It has evolved from a morphology-driven discipline to the multimodal assessment of CNS lesions, incorporating biochemistry (e.g., indicators of cell membrane synthesis) as well as physiologic parameters (e.g., hemodynamic variables)..Tumor cellularity, metabolism, and angi

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https://doi.org/10.1007/978-3-642-77405-8most lethal tumors with a very dismal prognosis, despite advances in standard therapy, including surgery, radiation, and chemotherapy. The median survival of patients with malignant gliomas has changed little in the last few years and is still measured in months. In an attempt to develop new therape

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Ravinder K. Goyal,Autar K. Mattooromoter methylation and clinical course in glioblastoma. While . promoter methylation analysis currently does not alter treatment of glioblastoma patients, mainly because of a lack of convincing therapy to radiotherapy and concomitant administration of alkylating drugs, there is increasing interest

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Ewald Blasius,Klaus-Peter Janzen recent years. There is growing evidence that many adult tissues contain a set of tissue stem cells, which might undergo malignant transformation while retaining their stem cell characteristics. These include the ability of indefinite self-renewal and the capability to differentiate into daughter ce

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Astrocytic Tumorsthe basic histological and epidemiological aspects of the different astrocytoma subtypes in adults. In addition, we summarize the key genetic alterations that have been attributed to astrocytoma patho-genesis and progression. Recent progress has been made by interpreting genetic alterations in a pat

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Molecular Pathology of Oligodendroglial Tumorsligodendrocytes (Bailey and Cushing 1926; Bailey and Bucy 1929). However, a convincing link between oligodendrocytes and oligodendrogliomas still needs to be shown. Oligoastrocytomas or mixed gliomas are histologically defined by the presence of oligodendroglial and astrocytic components. According

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Ependymal Tumorses. The scope of this chapter is to review the clinical and histo-logical features as well as the molecular genetics of ependymomas with special emphasis on their influence on tumor recurrence and prognosis. Furthermore, potential molecular targets for therapy are outlined.

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Surgical Management of Intracranial Gliomassue diagnosis, providing symptom relief, improving patient survival by reducing the tumor burden, and in rare cases even effecting a cure..A resection will reduce symptoms related to the mass effect of the tumor, and offers a good chance for seizure control. An increasing body of data suggests that