书目名称 | Glioma Signaling | 编辑 | Jolanta Barańska | 视频video | | 概述 | Gives updated as well as new chapters in this second edition.Provides new data concerning gliomas invasion and progression.Describes important topics concerning molecular mechanisms responsible for gl | 丛书名称 | Advances in Experimental Medicine and Biology | 图书封面 |  | 描述 | .Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumor, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. This book is a reference on cellular signaling processes regulating gliomas physiology and invasiveness. .The work is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides and formation of complex signaling cascades induced by growth factors, cytokines and cannabinoids. The second edition of the book enriched in new chapters provides a framework explaining how signal transduction elements may modulate numerous genetic and epigenetic alterations, describes the role of local microenvironment in cellular growth, progression and invasion and, in the light of extensive new results, presents perspectives concerning potential targets for gliomas therapy.. | 出版日期 | Book 2020Latest edition | 关键词 | secondary messengers; nucleotide receptors; tumor growth; tumor invasion; tyrosine kinase receptors; Rece | 版次 | 2 | doi | https://doi.org/10.1007/978-3-030-30651-9 | isbn_softcover | 978-3-030-30653-3 | isbn_ebook | 978-3-030-30651-9Series ISSN 0065-2598 Series E-ISSN 2214-8019 | issn_series | 0065-2598 | copyright | Springer Nature Switzerland AG 2020 |
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