书目名称 | Germline Stem Cells | 编辑 | Steven X. Hou,Shree Ram Singh | 视频video | | 概述 | Readily reproducible protocols for the manipulation of germline stem cells in model organisms.State of the art methods optimized by leading experts in germline stem cells.Identification and regulation | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | Stem cells are responsible for maintaining tissue homeostasis. They possess unlimited self-renewal potency. Through asymmetric cell division, a stem cell in adult tissues can produce an offspring that will maintain the stem cell populations and a daughter cell that will differentiate into various short-lived cell types to replace damaged or dying cells. Tumors may originate from a few transformed cancer stem cells. Stem cells have immense potential for therapeutic use in regenerative medicine and for developing anticancer therapies that specifically eliminate cancer stem cells. Germline stem cells are the source of human and animal reproduction. The knowledge gained from studying germline stem cells may find immediate application in preserving endangered wildlife, managing commercial livestock, overcoming fertility problems in humans, and treating testicular and ovary tumors. To make use of this potential, we have to learn how to isolate, characterize, and maintain germline stem cells. To isolate, characterize, and maintain stem cells, we must first understand the molecular parameters that define a germline stem cell and the mechanisms that regulate stem cell behavior. The protocol | 出版日期 | Book 2008 | 关键词 | Drosophila; In vitro culture; Reproductive system; Stem cell behavior; Vivo; cell lines; genes; regulation; | 版次 | 1 | doi | https://doi.org/10.1007/978-1-60327-214-8 | isbn_softcover | 978-1-61737-880-5 | isbn_ebook | 978-1-60327-214-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Humana Press 2008 |
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