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Titlebook: Germ Cell Tumours V; The Proceedings of t Patricia Harnden,Johnathan K. Joffe,William G. Jon Conference proceedings 2002 Springer-Verlag Lo

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Translational Implications of Ape1 in Germ Cell Tumours: Ape1 as a Therapeutic Targetsite. AP sites are generated from spontaneous and chemically initiated hydrolysis, ionizing radiation, UV irradiation, oxidative stress, oxidizing agents, and removal of altered (such as alkylated) bases by DNA glycosylases. In the latter case, this incision generates a normal 3′-hydroxyl group and
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https://doi.org/10.1007/b138547Traditional karyotypic analysis of adult male germ cell tumours (GCTs) performed in this and other laboratories revealed several chromosome abnormalities that may have roles in the aetiology and progression of this disease [1–3].
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Werte in Europa: Einheit in VielfaltAssociation with HLA, in particular class II genes (DQB1, DRB1), has been suggested as one of the genetic factors involved in TGCT development [1]. The present study used a marker haplotyping method in trios (parents or spouse and child) to replicate the previous findings, obtained through HLA typing.
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Harald Pfeiffer,Andreas SalewskiThere have been conflicting reports since 1985 as to the frequency and nature of HIV related testicular (HT) cancer. Two recent reports, and another large series confirm that testicular cancer is more common compared to age matched controls (relative risk 3.9), and seminoma occurs more frequently than non seminoma [1, 2].
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Europapolitik aus dem AusschussMicroinvasive testicular germ cell tumour (GCT) is defined as invasion of the interstitium by malignant germ cells without palpable tumour formation [1]. Microinvasive GCTs can also accompany overt tumours.
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Advances in the Understanding of Germ Cell Tumour BiologyTraditional karyotypic analysis of adult male germ cell tumours (GCTs) performed in this and other laboratories revealed several chromosome abnormalities that may have roles in the aetiology and progression of this disease [1–3].
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