Titlebook: Germ Cell Development in C. elegans; Tim Schedl Book 2013 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spri

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Germ Cell Apoptosis and DNA Damage Responses,, but also directly affect DNA repair, and a transient cell cycle arrest of mitotic germ cells. Finally, distinct pathways activate germ cell apoptosis in response to defects in meiotic recombination and meiotic chromosome pairing.

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Control of Oocyte Growth and Meiotic Maturation in ,, a cellular level, the responses include cortical cytoskeletal rearrangement, nuclear envelope breakdown, assembly of the acentriolar meiotic spindle, chromosome segregation, and likely changes important for fertilization and the oocyte-to-embryo transition. This chapter focuses on signaling mechani

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https://doi.org/10.1057/9781137371492 and the interplay of specific transcriptional activators. As sperm formation progresses, chromatin is ­systematically remodeled to allow first for the implementation of differentiation programs, then for sperm-specific DNA packaging required for transit of paternal genetic and epigenetic informatio