书目名称 | Genomics of Pattern Recognition Receptors | 副标题 | Applications in Onco | 编辑 | Anton G. Kutikhin,Arseniy E. Yuzhalin | 视频video | | 概述 | Summarizes the field and indicates key directions.Explores and analyzes genomic variations.With numerous tables presenting the data systematically.Includes supplementary material: | 图书封面 |  | 描述 | .This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.. | 出版日期 | Book 2013 | 关键词 | Cancer; Cardiovascular diseases; Immune response; NOD-like receptors; Pathogen-associated patterns; Toll- | 版次 | 1 | doi | https://doi.org/10.1007/978-3-0348-0688-6 | isbn_softcover | 978-3-0348-0794-4 | isbn_ebook | 978-3-0348-0688-6 | copyright | Springer Basel 2013 |
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