Titlebook: Genomics and Proteomics for Clinical Discovery and Development; György Marko-Varga Book 2014 Springer Science+Business Media Dordrecht 201

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Rapid Advances in the Field of Epigenetics,nd post-translational modification on histones, which consist chromatin, have been proved to mediate the epigenetic regulations. Then, DNA methyltransferases and histone deacetylases have been implicated in carcinogenesis to be attractive drug targets..More recently, the filed of epigenome is rapidl

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Pharmacogenomics in Drug Development,nucleotide polymorphisms, gene duplications, epigenetics and gene expression. Extensive interindividual differences in drug response and toxicity are observed in most disease areas and pharmacogenomics is one of the factors leading to this variability. In drug development, understanding the pharmaco

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Book 2014ho need a good understanding of genomics and proteomics within the clinical field. The book will also be targeted at a broad public as well as readers not specialized within this field..Dr. Marko-Varga is the head of the Head of Div. Clinical Protein Science & Imaging at the Biomedical Center, Dept.

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Genomics and Proteomics for Clinical Discovery and Development

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2213-2775 t a broad public as well as readers not specialized within this field..Dr. Marko-Varga is the head of the Head of Div. Clinical Protein Science & Imaging at the Biomedical Center, Dept.978-94-024-0743-3978-94-017-9202-8Series ISSN 2213-2775 Series E-ISSN 2213-2783

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Funktion und Gehalt von Kunst und Dichtung,dditional therapy and detecting recurrence (Fig. 9.1) (Ludwig and Weinstein 2005). Predictive biomarkers allow clinicians to assess clinical effects of chemotherapy and molecular targeted agents on response rate and survival time (Saijo 2012). The patients with poor responses have severe toxicities