Titlebook: Genomics Applications for the Developing World; Karen E. Nelson,Barbara Jones-Nelson Book 2012 Springer Science+Business Media New York 20

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,Biopsy Interpretation—Light Microscopy,hnological disparities, in addition to the genetic heterogeneity and population diversity. Language distinguishes the Portuguese-speaking Brazilians from the Spanish-speaking peoples living in all other Latin American nations. Although Native American, European, and sub-Saharan African biogeoghraphi

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The Skin and Subcutaneous Tissues,atment that is based on a patients’ genetic status. Africa, on the other hand, has lagged behind in these advances, but recent developments are showing great potential for pharmacogenomics research and clinical applications on the continent. The genetic variability of African populations is proving

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Rahul Gupta,Liza Das,Pinaki Dutta largest tropical forest cover (>6 million km., corresponding to approximately 30 times the area of the United Kingdom or approx. 20 times the area of Germany) and one of the largest marine realms (>4 million km.) of the planet. The diversity of biomes (e.g., the Amazon and Atlantic Forests, Souther

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The Genomics of Leprosytic biology and has helped develop promising immunological and nucleic-acid-based tools for more efficient and sensitive diagnosis. Comparative genomics of various . strains has been useful in developing robust and reliable molecular epidemiological tools to monitor the transmission dynamics of the

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New Tuberculosis Drugse to at least INH and RIF) and extensively drug-resistant (XDR – resistance to INH and RIF plus resistance to a fluoroquinolone and one or more of the injectable drugs: kanamycin, amikacin, and capreomycin) strains of TB has increased the need to discover and develop new and improved therapies for t

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Pharmacogenomic Applications in the Developing World: The American Continentargest world economies, whereas their neighbors, Uruguay and Guatemala rank 78th and 77th, respectively (Table 10.1). However, a considerably different picture emerges from the GDP per capita, with Brazil, Mexico, Uruguay, and Guatemala appearing in the 71th, 59th, 60th, and 116th positions, respect

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Pharmacogenomics in Africaations distinct from that of Asian and of Caucasian populations. Clinical studies on the effect of the CYP2B6G516T variant on efavirenz concentrations were predictive of a dose reduction to a third of the standard dose in patient homozygous of the variant. This could have significant effects on the

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