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Titlebook: Genomic Medicine; A Practical Guide Laura J. Tafe,Maria E. Arcila Book 2020 Springer Nature Switzerland AG 2020 hematopoietic disorders.Pha

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发表于 2025-3-21 18:32:14 | 显示全部楼层 |阅读模式
书目名称Genomic Medicine
副标题A Practical Guide
编辑Laura J. Tafe,Maria E. Arcila
视频videohttp://file.papertrans.cn/383/382900/382900.mp4
概述Provides a user-friendly, succinct reference.Synthesizes important major updates and guidelines in this field.Written by experts in the field
图书封面Titlebook: Genomic Medicine; A Practical Guide Laura J. Tafe,Maria E. Arcila Book 2020 Springer Nature Switzerland AG 2020 hematopoietic disorders.Pha
描述The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care..This text focuses on clinical utility and validity and serves as an “owner’s manual” in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will fi
出版日期Book 2020
关键词hematopoietic disorders; Pharmacogenomics; Immunotherapy; drug targets; epigenetics; FISH
版次1
doihttps://doi.org/10.1007/978-3-030-22922-1
isbn_ebook978-3-030-22922-1
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

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Next-Generation SequencingNGS wet lab and dry lab processing. The library preparation process prepares the substrates to be sequenced through nucleic acid isolation, fragmentation, isolation, end repair, adapter ligation, size selection, and target enrichment. Several types of sequencers exist, with sequencing by ligation, s
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Cell-Free DNA Testingome a ubiquitous companion modality for diagnosis, prognosis, treatment selection, and recurrence detection for myriad medical conditions. In this chapter, we aim to provide an overview of current and potential cfDNA applications, specimen collection and assay design considerations, and technology u
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Interpreting Genomic Reports cover several or most genes (gene panels), the exome, or the whole genome and have the potential to identify multiple variants. To avoid errors in interpretation, clinicians need to familiarize themselves with the report format and understand each section of the report. In this chapter, we provide
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GI Including GISTmicrosatellite instability, KRAS and BRAF mutations and . gene amplifications. Other molecular biomarkers are emerging as clinically important as new resistance mechanisms are identified and/or as new targeted therapies are developed. In gastrointestinal stromal tumors (GISTs), molecular tests are c
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