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Titlebook: Genomic Diversity; Applications in Huma Surinder S. Papiha,Ranjan Deka,Ranajit Chakraborty Book 1999 Springer Science+Business Media New Yo

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Molecular Anthropology,ient specimens and DNA extracts with modern DNA is more widespread than is generally acknowledged and remains a significant problem in aDNA analysis. Furthermore, studies of human aDNA are uniquely sensitive to contamination due to the continual presence of potential contamination sources and these
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Worldwide Distribution of a Polymorphic,Insertion in the Progesterone Receptor Gene,s per haploid genome. Of this, only a few thousand are thought to be polymorphic exhibiting both the insertion and lack of insertion alleles. The probability of independent.insertion events at the same site is remote. The ancestral state of an.repeat represents the absence of the insertion while the
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Statistical Issues Regarding the Use of Microsatellite Loci for Molecular Anthropological Studies,s, the microsatellites have been the most popular in their use for gene mapping, studying evolutionary relatedness of populations, identifying the source of biological specimens and parentage testing. In this presentation the biological features of repeat polymorphism are briefly reviewed to illustr
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Trinucleotide Repeats, Genetic Instability and Variation in the Human Genome,known disease. These findings imply that the process of instability is not exclusively a disease-associated phenomenon. In this chapter, we discuss some of the population genetic properties of these loci, with a general emphasis on questions relating to maintenance of the expanded alleles in human populations.
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