Titlebook: Genomic Disorders; The Genomic Basis of James R. Lupski,Pawel Stankiewicz Book 2006 Humana Press 2006 DNA.chromosome.diseases.evolution.gen

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犬儒主义者

The CMT1A Duplicationer by Botstein and colleagues (.) proposing the genetic mapping of human “disease genes” using linked restriction fragment length polymorphisms (RFLPs) to position the gene within the human genome and indeed became very excited as a graduate student when Gusella’ s paper (.) appeared in Nature linki

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The Impact of LINE-1 Retro transposition on the Human Genomed to genome diversification and individual genetic variation by serving as insertional mutagens and by providing recombination substrates either during or long after their insertion. L1 retrotransposition also generates genomic variation by mobilizing DNA derived from its flanks, non-autonomous retr

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