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Titlebook: Genomic Approach to Asthma; Xiangdong Wang,Zhihong Chen Book 2018 Springer Nature Singapore Pte Ltd. 2018 Asthma Genetics.Epigenomics Stud

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Pharmacogenetic Study in Asthma,riability gene. The pharmacogenetics goal of asthma is to personalize asthma pharmacotherapy and reduce the asthma burden. The present manuscript discusses the coding sequences or regulatory regions of genes that encode proteins involved in asthma pharmacological responses.
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Protein and Post Translational Modification in Asthma,ates updated approaches in proteins and PTM detection and associating biomarkers of asthma. We focus on approaches such as Mass Spectrometry (MS), NMR, and microarray platforms. Concepts of protein and PTMs may provide new insights in searching potential clinical biomarkers in asthma.
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MicroRNA and Its Application in Asthma Studies,ody. Recent studies have found that a large number of asthmatic patients have abnormal miRNA expression, and that miRNA has played a key role in asthma, including in regulating the immune function, airway inflammation, and airway remodeling. Therefore, this article reviews the application of microRNA in asthma.
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https://doi.org/10.1007/978-3-031-47630-3that epigenetic variation plays an important role in asthma development and severity, possibly through interactions with genetic variations and gene expression. The utilization of epigenetic variation in combination with clinical phenotypes and other molecular markers in separating asthma patient subgroups has been suggested.
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Merchant Capital and Underdevelopment,ect asthma and manage its treatment. In this chapter, we review the current literature on the metabolomics studies to gain knowledge of the pathophysiological basis of asthma and find potential metabolic biomarkers associated with this disease, which may help in diagnosis and therapeutic strategies.
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