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Titlebook: Genome-Wide Association Studies; Tatsuhiko Tsunoda,Toshihiro Tanaka,Yusuke Nakamura Book 2019 Springer Nature Singapore Pte Ltd. 2019 Geno

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https://doi.org/10.1007/978-3-662-40977-0henotypic traits and diseases. These exciting advances were originally enabled by the results from the Human Genome project (1990–2003) that allowed the completion of the first genome-wide association study in 2002 and led to the development of haplotype maps of the human genome. Technological advan
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https://doi.org/10.1007/978-3-662-40976-3dustrial countries. The pathogenesis depends on multiple interactions on an environmental and genetic basis. As genetic heritability of CAD comprises ~ 50% of the pathogenesis, elucidating the detailed genetic architecture of CAD would facilitate development of a future precision medicine. Initially
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,Die großen Umwälzungen der Volksernährung,ental factors. A limited number of disease susceptibility genes, including those of the major histocompatibility complex have been known to exist for several decades. After these eras, genome-wide association studies have been used for more than 10 years to identify susceptibility genes for certain
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Deutschlands zukünftige Bildungsstruktur Infectious diseases are caused by bacteria, viruses, parasites, or fungi and these pathogens are considered as one of the environmental factors of disease onset. The first GWAS in infectious disease was reported in 2007 for acquired immunodeficiency syndrome (AIDS). More than 80 GWASs have since be
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Book 2019s and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and disease diversity. In Genome-Wide Association Studies, experts in the field explore in depth the impacts of GWAS
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