书目名称 | Genome Editing | 编辑 | Kursad Turksen | 视频video | | 概述 | Presents the state of the science for CRISPR-Cas9 an increasingly hot field.Will include chapters on current controversies and future directions.Chapter authors are leaders in their fields and present | 图书封面 |  | 描述 | This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of controversies and future directions..Genome Editing. is an essential, of-the-moment contribution to this rapidly growing field. Drawing from a wealth of international perspectives, it presents novel techniques and applications for the engineering of the human genome. This book is essential reading for all clinicians and researchers in stem cells, regenerative medicine, genomics, biochemicaland biomedical engineering- especially those interested in learning more about genome editing and applying it in a targeted, specific way.. | 出版日期 | Book 2016 | 关键词 | CRISPR; ESC; iPSC; nucleases; stem cells | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-34148-4 | isbn_softcover | 978-3-319-81687-6 | isbn_ebook | 978-3-319-34148-4 | copyright | Springer International Publishing Switzerland 2016 |
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