Titlebook: Genetics of Melanoma; Carlos A. Torres-Cabala,Jonathan L. Curry Book 2016 Springer Science+Business Media New York 2016 genetics.melanoma.

遭遇

Die Grundlagen der Untersuchungion tool to predict prognosis and guide patient management continues to be histologic examination. Thus, this chapter describes the most important histologic factors that allow to render a diagnosis of melanoma and related lesions, with special emphasis to the AJCC/CAP classification of melanoma.

受辱

https://doi.org/10.1007/978-94-009-6074-9d may represent a crucial target for combination therapy. This chapter will describe the components of the PI3K-AKT pathway, highlight their role in cellular physiology and melanoma pathogenesis, and examine their potential for molecular-targeted therapy.

acrimony

他一致

The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanomaors has become a critical area of research. This chapter describes the immunoregulatory mechanisms in the melanoma tumor microenvironment and how positive and negative signaling elements can be harnessed to facilitate enhanced anti-tumor immune responses through immunotherapy.

Terminal

Intrepid

符合国情

Targeted Therapy in Melanomaanisms of resistance are presented. Lastly, ./. mutations, found in up to 80 % of uveal melanoma patients, are detailed, and new insights into the role of the PTEN/PI3K/AKT/mTOR pathway are discussed.

Between

Interlocking

Molecular Platforms for Melanoma Mutation Analysistional analysis are becoming standard of care in melanoma as the detection of these mutations will contribute to the development of molecular classification of melanocytic tumors and guides through choosing the most appropriate therapy in the era of personalized medicine.

无能力之人

Book 2016genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal expe