书目名称 | Genetics of Immunological Diseases |
编辑 | Beverly Mock,Michael Potter |
视频video | |
丛书名称 | Current Topics in Microbiology and Immunology |
图书封面 |  |
描述 | The development of innovative molecular techniques such as pulse-field gel electro phoresis, cDNA subtraction libraries and chromosome hopping libraries coupled with the increasing popularity in the prospect of sequencing mammalian genomes, has triggered a resurgence of interest in finding and characterizing genes that playa role in modifying immune processes and diseases. Genetically defined strains of mice (e. g. , inbred strains and recently derived stocks of wild mice) provide ideal models for examining the genetic control of diseases as a result of their syntenic relationship with man in genetic composition as well as linkage conserva tion. Due to the relative ease of producing a specific genotype via appropriate breeding schedules, murine models may provide the only hope for unravelling those complex disease processes under mUltigenic control. This issue of CTMI is a collection of papers on the characterization and mapping of genes involved in mutations and dysregulated immune responses which produce disease phenotypes. These papers were presented at a workshop which was devoted to examining reverse genetic approaches at localizing, cloning and characterizing genes involved |
出版日期 | Conference proceedings 1988 |
关键词 | diseases; genetics; immune response; infectious disease |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-50059-6 |
isbn_softcover | 978-3-642-50061-9 |
isbn_ebook | 978-3-642-50059-6Series ISSN 0070-217X Series E-ISSN 2196-9965 |
issn_series | 0070-217X |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |