| 书目名称 | Genetic factors in coronary heart disease |
| 编辑 | Uri Goldbourt (Professor of Epidemiology and Preve |
| 视频video | |
| 丛书名称 | Developments in Cardiovascular Medicine |
| 图书封面 |  |
| 描述 | Incidence and mortality of atherosclerosis and coronary heartdisease (CHD) vary considerably among races, populations and ethnicgroups. Some individuals with low levels of risk factors succumb earlyto disease while many others with a high risk profile do not. CHDclusters in families and is manyfold increased in first degreerelatives of persons with an early onset of the disease. Such studiesprovide compelling evidence of the high degree of heritability of CHDand its risk factors. .This book consolidates the available evidence for the roles ofgenetics in atherosclerosis, its correlates and its sequelae. Itpresents and discusses the methodology currently used to elucidate therole of genetics. Separate parts focus on evidence of familialaggregation and ethnic variability of the disease and on monogenic andpolygenic inheritance modes including all the recent findings andinnovation. The book also contains chapters on the genetic aspects ofvessel wall processes, such as early structural findings inhistological studies and the variability of coronary anatomicpatterns. Polymorphisms at the DNA level (RFLP) are detailed andreviewed. Directions for future research in the exciting and fastdev |
| 出版日期 | Book 1994 |
| 关键词 | Diabetes; biostatistics; cardiovascular; epidemiology; genetic epidemiology; methodology |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-011-1130-0 |
| isbn_softcover | 978-94-010-4494-3 |
| isbn_ebook | 978-94-011-1130-0Series ISSN 0166-9842 |
| issn_series | 0166-9842 |
| copyright | Springer Science+Business Media Dordrecht 1994 |
发表于 2025-3-21 17:03:03
