书目名称 | Genetic Susceptibility to Cancer | 编辑 | Seymour Garte | 视频video | | 丛书名称 | Developments in Oncology | 图书封面 |  | 描述 | Despite recent progress in many areas of treatment and control,cancer remains a frightening threat to everyone. While scientists haveknown for decades that the majority of human cancers are caused byenvironmental agents such as radiation and the chemicals in cigarettesmoke, not everyone who smokes gets lung cancer. Furthermore, manypeople who assiduously avoid all possible risk from smoking, diet, andpollution still succumb to some form of cancer later in life. Doesthis mean that there is an element of blind chance in the underlyingmechanisms of human carcinogenesis? To what extent do geneticinfluences play a role in determining the cancer risk of individuals?.A number of `cancer families‘, in which several closely relatedindividuals have suffered from various specific forms of cancer, havebeen studied by genetic epidemiologists. However, for the majority ofcancer cases, little or no discernible genetic influence or familyhistory is found. Recent research has discovered that for many ofthese `sporadic‘ (non-familial) cancer cases, defects or aberrationsin certain metabolic genes not previously associated with geneticcancer risk may contribute to either causing the disease or at lea | 出版日期 | Book 1998 | 关键词 | Tumor; cancer; carcinogenesis; genes; health; oncogene | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4615-4989-5 | isbn_softcover | 978-1-4613-7265-3 | isbn_ebook | 978-1-4615-4989-5 | copyright | Springer Science+Business Media New York 1998 |
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