Titlebook: Genetic Research in Psychiatry; “2. Münchner Genetik Julien Mendlewicz,Hanns Hippius (Head of Dept. of Conference proceedings 1992 Springe

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Family Studies of Affective Disorders with 11p15.5 DNA Markers,usive. The remarkable success with which the classical logarithm of odds (lod) score method has contributed to the localization of loci for numerous diseases has led many authors to apply this strategy to complex illnesses such as affective disorders. Most pertinent was the study conducted by Egelan

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Clinical Phenotypes: Problems in Diagnosis,m in psychiatric diagnosis no longer can be said to be unreliability. Fortunately, substantial and impressive progress has been made during the past two decades. We now face a more complex and perhaps less tractable issue — the validity of diagnosis. One reason to be less sanguine about progress in

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Biological Markers in Schizophrenia and the Affective Psychoses,ditions which are classified almost entirely by signs and symptoms observed and elicited at clinical interview. The absence of objective biological traits shown to be associated with illness ensures a continuing debate about the validity of current classifications. It is probable that what we call s

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Twin Research,hrough observations of higher concordance for monozygotic than for dizygotic twins. In the recent era of molecular genetics, twin research may appear outdated, as an almost historical approach. Twin research, however, is still contributing important information to research on the molecular level, to

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978-3-642-46764-6Springer-Verlag Berlin Heidelberg 1992

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Neil Thompson,Michael Murphy,Steve Stradling syndrome) using molecular genetic techniques has stimulated several scientists to use a similar approach to Alzheimer’s disease (AD), the major cause of senile dementia in the Western population (Davies 1986).

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https://doi.org/10.1007/978-90-6704-930-6em, and desensitization of these receptors. He further reported about an observation which suggests that point mutations in these receptors might contribute to changing their function and might thus be highly interesting for CNS disorders.