Titlebook: Genetic Polymorphism and cancer susceptibility; Aga Syed Sameer,Mujeeb Zafar Banday,Saniya Nissar Book 2021 The Editor(s) (if applicable)

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Single Nucleotide Polymorphisms and Pharmacogenomics,cules such as drug-metabolizing enzymes, drug transporters, and drug targets. Single nucleotide polymorphisms (SNPs) are very helpful in determining the susceptibility of individuals to different diseases and drug reaction. These polymorphisms are the most prevalent in the genome of humans and accou

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Impact of MicroRNA Polymorphisms on Breast Cancer Susceptibility,orphisms in miRNAs are even found to be associated with breast cancer and evidential support suggests that they substantially increase breast cancer susceptibility. In this chapter, we will summarize and discuss the most recent shreds of evidence explaining the role of miRNAs and the poly-miRs’ in c

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From Inflammation to Cancer: Role of Genetic Polymorphisms of Inflammatory Pathway Molecules in Gassociated with gastric cancer; most of them occur within immune response genes. This book chapter will discuss recent pathological and epidemiological aspects from the perspective of polymorphisms and gastric carcinoma. It will also summarize our understanding of the genetic basis of gastric cancer,

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Genetic Polymorphisms of Essential Immune Pathogenic Response Genes and Risk of Cervical Cancer,otal risk factor for the initiation and progression of CC. However, the transition of CC from the foundation of HPV infection to preinvasive lesions and finally to an invasive cancer takes decades. The contribution of genetic variation, in particular gene polymorphism, towards modifying the cervical

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The Role of Toll-Like Receptor (TLR) Polymorphisms in Urinary Bladder Cancer,range of risk factors predisposing people to BCa, the feature of single nucleotide polymorphism within the toll-like receptor (TLR) genes is recognized as an important one. The feature of polymorphism in TLR genes has been investigated in different types of cancers including breast and prostate canc

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Genetic Polymorphism and Their Role in Lung Cancer,hways, immune response/inflammatory pathways, cell cycle regulatory pathways, etc. The SNPs not only affect the transcription of genes and structure and function of the proteins, but also have a potential role in diagnosis, prognosis, and even treatment selection and overall survival of the patients

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Das Neue Bewußtsein im Unternehmenations which accounts for only 0.1–0.4% of the total genomic DNA or genome. These genetic variations are generally described in terms of mutation and genetic polymorphism. Mutation is defined as the irreversible sequence variation in the DNA which essentiality encompasses all types of variations occ

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Katharina B. Springer,Ragnar K. Kinzelbachesses. They are capable of altering the hallmarks of cancer and hence are considered as prominent cancer biomarkers. More recently, the microRNAs related polymorphism, i.e. single nucleotide polymorphisms (SNPs) or (poly-miRs’) are reported and are exhaustively being studied. SNPs or (poly-miRs’) mi

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