Titlebook: Genetic Causes of Cardiac Disease; Jeanette Erdmann,Alessandra Moretti Book 2019 Springer Nature Switzerland AG 2019 induced pluripotent s

metabolism

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podiatrist

AXIOM

抚育

Controlling im Gesundheitswesen risk factors are a leading cause of death and morbidity in the world [1–3]. According to World Health Organization estimates, CVDs are responsible for 151,377 million disability-adjusted life years (DALY). DALY is the number of years lost because of ill health, disability or premature death. Corona

臆断

https://doi.org/10.1007/978-3-658-45895-9ew recent findings on the genetic basis and inheritance patterns of CHD. Rather than provide lists of identified genes, instead we offer a conceptual framework to understand the relationship between genetic variation and CHD. We review recent studies utilizing contemporary techniques, some of which

装勇敢地做

https://doi.org/10.1007/978-3-7091-6219-40 people [1–3]. Inherited in an autosomal-dominant fashion, it is associated with lifelong, severe elevations in low-density lipoprotein-cholesterol (LDL-c) levels. Individuals with FH have a markedly elevated risk of premature ischemic heart disease, 5–20-fold higher than the general population [4–

装勇敢地做

Edmond Irani Liu,Matthias Althoffd. This includes tens of thousands of RNAs sized larger than 200 nucleotides that are not translated into proteins and are referred to as long noncoding RNAs (lncRNAs). Until now, only a few of these lncRNAs have been functionally characterized. Here we highlight lncRNAs related to cardiovascular ph

Nonconformist

Corona und mediale Öffentlichkeitenere with these devastating diseases is limited. Cardiomyopathies, which are mainly due to genetic causes, make a significant portion of heart failure. Current pharmacological treatment of cardiovascular diseases focuses on symptoms rather than the underlying cellular mechanisms, and the gaps in our

胶水

conifer

Petter Gottschalk,Christopher Hamertoncells (hiPSCs) from diseased and healthy individuals, the discovery of the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) genome editing system, and the possibility to identify disease-related genetic variants in human populations in genome-wide associa