Titlebook: Genes, Development and Cancer; The Life and Work of Howard D. Lipshitz (Senior Scientist and Head, Pro Book 2004 Kluwer Academic Publishers

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Pseudoallelism and Gene Evolutionts, may provide clues to the mode of origin of new kinds of genes.Our underlying thesis will be that in those instances of pseudoallelism in which there is evidence for close functional similarity among the component genes we may come close to seeing the direct results of a process which produces ne

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The Theory and Application of a New Method of Detecting Chromosomal Rearrangements in ,rom nuclear detonations. The method, itself, is an outgrowth of studies of the bithorax pseudoallelic genes near the middle of the right arm of the third chromosome (Lewis, 1951). It will be called the “bithorax” method. Results of applying it to the detection of X-ray induced rearrangements will be

LAPSE

Some Aspects of Position Pseudoallelismnctional aspect will be the central theme of this paper. Attention will be focused chiefly on examples of “position pseudoallelism;” namely, those cases in which there is a position effect or phenotypic difference between the “cis-type” (./++) and “trans-type” (.+/+.) of double mutant heterozygote.

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Lewis and the Genetic Control of Developmentespecially by chemistry may lead to the discovery of the physiological action of the genes” (Morgan, 1923). He went on to argue in favor of the fundamental role that genes must play in controlling development: “The embryologist observes the developmental changes taking place in the cytoplasm in the