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Titlebook: Generalized Epilepsy; Neurobiological Appr Massimo Avoli,Pierre Gloor,Robert Naquet Book 1990 Birkhäuser Boston, Inc. 1990 PET.brain.cortex

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书目名称Generalized Epilepsy
副标题Neurobiological Appr
编辑Massimo Avoli,Pierre Gloor,Robert Naquet
视频video
图书封面Titlebook: Generalized Epilepsy; Neurobiological Appr Massimo Avoli,Pierre Gloor,Robert Naquet Book 1990 Birkhäuser Boston, Inc. 1990 PET.brain.cortex
描述In recent years there has been intense interest in the basic mechanisms of epilepsy. Many symposia and monographs have been devoted to this topic. These reviews, however, have focused almost exclusively on studies performed in models of partial (or focal) epilepsy. It was natural that scientists interested in the fundamental mechanism of epileptogenesis at the cellular level were attracted to work on models in which the epileptogenic dysfunction could be confined to ever-smaller populations of neurons. Many of the most illuminating studies done in this field in the recent past have been carried out in vitro on brain slices or on dissociated neuronal cultures. Much valuable insight into the mechanisms of epileptogenesis has been obtained in this manner. One cannot, however, automatically assume that mechanisms elucidated in such exquisitely "focal" models are applicable to forms of epilepsy in which seizures from their very start involve the entire brain. One of the most difficult questions that arises in this context is how epileptogenic dysfunction, which can be understood in terms of mechanisms involving a few contiguous cells, can lead to what appears to be a simultaneous onset
出版日期Book 1990
关键词PET; brain; cortex; electroencephalography (EEG); epilepsy; neurons; physiology; positron emission tomograp
版次1
doihttps://doi.org/10.1007/978-1-4684-6767-3
isbn_softcover978-1-4684-6769-7
isbn_ebook978-1-4684-6767-3
copyrightBirkhäuser Boston, Inc. 1990
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书目名称Generalized Epilepsy影响因子(影响力)




书目名称Generalized Epilepsy影响因子(影响力)学科排名




书目名称Generalized Epilepsy网络公开度




书目名称Generalized Epilepsy网络公开度学科排名




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书目名称Generalized Epilepsy读者反馈学科排名




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The Relationship Between Sleep Spindles and Spike-and-Wave Bursts in Human Epilepsyd by Jasper and Kershman in 1941. Subsequently, Jasper and Droogleever-Fortuyn (1947) found that cortical spike-and-wave complexes could be elicited by stimulating the intralaminar system of the thalamus, a system that has been shown to be the primary substrate for the generation of sleep spindles (
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Membrane Properties of Cat Betz Cells Studied In Vitro seizures were first described (Matsumoto and Ajmone Marsan, 1964a, b). These sometimes spirited discussions were based, appropriately, upon the known mechanisms for neuronal excitability and synaptic transmission. But, even the elegant axon model of Hodgkin and Huxley (1952) and the mechanisms for
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Excitant Amino Acids in Epilepsytes in many brain regions (see Hicks et al., 1987; Cavalheiro et al., 1988). It has also become increasingly obvious that these EAAs may also play an important role in pathological conditions in the central nervous system (CNS). A considerable amount and diversity of evidence has been obtained to su
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Possible Epileptogenic Consequences of Misused GABAergic Relationships (Brailowsky et al., 1987; Fukuda et al., 1987; Silva-Barrat et al., 1988). An implanted cannula connected to osmotic minipumps provides a simple method for infusing solutions inside the cerebral tissue for several days, with a delivery rate slow enough to prevent extensive cellular damage (Fukuda e
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In Vitro Electrophysiology of a Genetic Model of Generalized Epilepsyystem, where the entire phe-notype of the disease is expressed, to simpler parts of this system, which one can more easily investigate. The validity of a reductionist approach seems to depend on an inverse inductive way of using the more precise information gained at the lower level of organization,
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