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Titlebook: General Principles and Procedures; R. D. O’Brien Book 1979 Springer Science+Business Media New York 1979 ATP.Lipid.biochemistry.cell membr

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The Pharmacon-Receptor-Effector Concept,ecular complexes present in the biological object. The same holds true for endogenous bioactive agents such as hormones, neurotransmitters, etc. Often these . have their molecular sites of action, referred to as their specific receptors, located on the outer cell membrane (Lefkowitz ., 1976). They t
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Distinction of Receptor from Nonreceptor Interactions in Binding Studies, been developed to measure with confidence the binding of highly radioactively labeled probes to quantitatively small numbers of high-affinity binding sites, which in most cases represent pharmacologic receptors of interest. Now, these techniques are being employed to study . for an ever-burgeoning
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Problems and Approaches in Noncatalytic Biochemistry,pled with the vigorous explorations of metabolic pathways that grew out of the nutritional beginnings of biochemistry, led to the extraordinary depth of knowledge that we have now, both of the routes of metabolism and the enzymes which catalyze the individual steps in these routes, constituting a ne
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The Pharmacon-Receptor-Effector Concept,ase of the interaction of steroid hormones and their specific proteins in the cytoplasm, is involved in the transduction of information to the cell nucleus. The presence of specific receptor for the bioactive agents either on the outer cell membrane or in the cytoplasm of only particular tissue cell
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Kinetics of Cooperative Binding,ential equations for labeled and unlabeled ligand binding to a single class of homogeneous cooperative sites are formulated and the exact analytical solutions obtained. Properties of the model are examined in several coordinate systems, including the titration curve, Hill plot, and Scat-chard plot.
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