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Titlebook: General Pharmacology; A. J. Clark Book 1970 Springer-Verlag Berlin Heidelberg 1970 Hand.Pharmakologie

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Action of Heavy Metals on Enzymes in vitro and in vivo,heavy metals on living cells. Furthermore the heavy metals are particularly favourable drugs for quantitative measurement, and since their action on enzymes has been studied intensively the evidence provides an instructive basis for the consideration of their action on living cells.
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Time-concentration Curves,le formulae, but that closer examination of the processes involved showed that the processes in most cases were of a complex chain character and that the theoretical significance of the formulae was very doubtful.
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Relation Between Various Types of Curves Expressing Response of Cells to Drugs,macological responses can be interpreted as expressions of variation. In support of this hypothesis it can be pointed out that growth must tend to produce skew variation in any population as regards many of its characteristics.
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Qualitative Aspects of Drug Antagonism,neral rules discernible and that every cell-drug system appears to be a law unto itself. In the case of drugs which have sharply specific actions, it is common to find that the activity even of optical isomers differs widely, but on the other hand, drugs of widely different structure may have a similar action.
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The following three chapters (8, 9 and 10) give an account of the manner in which the actions of drugs on cells can be classified according to the relations observed between the concentration of the drug and the action produced. This relation has been chosen as the basis of classification for the following reasons.
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,The Chinese National People’s Congress,The rate of response of a tissue to the action of a drug can be studied in two way:
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